Sermorelin: Sermorelin is a Growth Hormone‐Releasing Hormone (GHRH) analog that increases your body’s potential to produce more natural Human Growth Hormone (HGH). This will slow the aging process while increasing lean muscle, energy, and sex drive. Sermorelin is injected daily just beneath the skin before bed since HGH is produced during sleep. Sermorelin will also help with increasing muscle strength and stamina, burn fat, improve the quality of sleep, enhance the appearance of the integumentary system (skin, hair, and nails), and provide a variety of other benefits. Many patients have reported experiencing some, if not most of these results.
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What are the benefits of Increased HGH Production via Sermorelin? |
| · Increased structural integrity on the bones with improved calcium retention |
| · Improved quality of sleep predicated by increased REM Sleep |
| · Boosted immune health |
| · Higher levels of stamina |
| · Improved muscular strength |
| · Thicker, fuller hair |
| · Enhanced emotional health with increased vitality and energy |
| · Improved cardiac function |
| · Speedier physical rehabilitation from surgery and injury |
| · Increased metabolism which burns adipose fat |
| · Smoother, tighter skin |
| · Increased muscle mass |
| · Enhanced libido and restored sexual ability |
| · Improved cognition |
| · Enhanced renal function |
Sermorelin Acetate Therapy
With Sermorelin Acetate Therapy, it is possible to restore youthful vitality and alleviate the effects of the aging process that result from Human Growth Hormone Deficiency. Sermorelin is a safe and effective hormone substitute that has the capability to naturally stimulate the Human Pituitary Gland in order to encourage the secretion of our own internal stores of Human Growth Hormone.
HGH is created by endocrine organs known as Somatotrophs located in the Anterior Pituitary. Although as we grow older, the body drastically slows down the production of HGH over time, the Somatotrophs never lose their ability to produce healthy levels of HGH. This is why Sermorelin Injections are an effective treatment for Growth Hormone Deficiency.
What is Sermorelin?
Sermorelin is the bio-synthetic form of a hormone naturally produced by the hypothalamus, known as Growth Hormone-Releasing Hormone. GH-RH is the means by which the brain sends a request to the pituitary to release HGH. GH-RH is delivered from the Hypothalamus to the Pituitary Gland via a pathway of blood vessels known as the Hypophyseal Portal System.
How is Sermorelin different from Bio-Identical HGH?
Unlike Bio-Identical Human Growth Hormone Replacement Therapy, Sermorelin Acetate is not structurally identical to GH-RH, but Sermorelin Acetate is functionally capable of producing the same biological effect on the body that is achieved naturally through GH-RH. Sermorelin Acetate is a truncated form of GH-RH, which means that the bio-synthetic hormone is structurally identical to the active portions of the GH-RH molecule while omitting portions of the molecule that are inert and do not encourage the release of HGH. Although the Sermorelin molecule is not naturally produced by the body, there are no adverse effects as with exogenous HGH. The treatment is perfectly safe.
HGH Decline Begins around Thirty
Adult Human Growth Hormone production reaches its peak by the time we reach the age of around twenty. Over the course of our twenties, we maintain high levels of HGH production which help us sustain ourselves physically, cognitively, and psychologically. By the time we reach the age of thirty, however, Growth Hormone Production starts to decline at a slow, yet the insipid rate of one to two percent each year.
Although this may not sound like a significant amount at first, this amounts to an average reduction in endogenous HGH production of around 14% every ten years! By the time a decade of decline has occurred, the human body only produces 40% of the Human Growth Hormone emitted during the period of peak production in our early twenties.
Symptoms of HGH Deficiency
This decline in HGH secretion does not come without significant health consequences. HGH Deficiency is correlated with a number of symptoms and syndromes that we take for granted as simply a part of the aging process, such as:
- Immune Suppression
- Decreased Cognitive Sharpness
- Wrinkles and Deep Lines
- Increased Adipose Fat, Especially around Midsection
- Reduced Libido
- Fatigue, Reduced Willpower & Motivation
Benefit of Sermorelin Vs. Other Treatments
Although HGH Hormone Replacement Therapy is a safe and effective means of restoring healthy Human Growth Hormone Levels, Sermorelin Acetate Injections completely eliminate the risk of overdose while encouraging the Pituitary Gland to be responsible for the dispensation of HGH rather than self-administration techniques. Sermorelin Acetate presents no risk of HGH Overdose because HGH production by the pituitary is down-regulated by effective biological negative feedback mechanisms.
Sermorelin and Somatostatins
When the brain feels that the human body has a sufficient amount of Human Growth Hormone necessary to maintain optimal health and hormone balance, the hypothalamus releases the inhibitory hormone Somatostatin, which blocks the uptake of Sermorelin and GH-RH by the Hypothalamus, preventing the brain from overloading the body with excess HGH. Because of the effectiveness of Somatostatin at effectively regulating the pituitary, the risk of Growth Hormone Overdose Via Sermorelin Injection is nearly impossible
Clinical Body Fat Reduction Using Sermorelin
Clinical trials show that after a single year of Sermorelin Acetate Therapy, it is possible to achieve a 20% reduction in adipose fat tissue. The majority of this fat tissue is eradicated from the midsection. Fat from the waist, hips, and stomach declines by around 30% while weight loss occurs via marginal areas of body fat such as the legs, arms, neck, and chest at a mass percentage of around 13%.
Sermorelin is Delivered Via Injection
Sermorelin Acetate is a low-risk treatment that is delivered via small injections just below the top layers of the skin, known as subcutaneous injection. These shots are simple to administer and patients generally perform their own injections in the privacy of their own homes or offices.
The Effect of Age On GH-RH Production
GH-RH is released at its highest rates during our youth, which corresponds directly with the rate at which our pituitary releases HGH at its most abundant. As we grow older, GH-RH levels start to decline, leading directly to a deficiency of Human Growth Hormone which speeds up the aging process and reduces overall health and well-being as a result. HGH Deficiency is also referred to as Hypopituitarism, relating to the suppression of pituitary function that causes the organ to release insufficient levels of vital Growth Hormone.
Phases of HGH Decline
At first, the effects of hypopituitarism are qualitative in nature and relatively hard to measure, yet vivid to experience. Low HGH first affects energy levels, which can affect overall motivation and suppress innate desires. After energy levels start to decline, the body starts to experience greater levels of fatigue on a physical level. Aside from being sapped of mental energy, the human body loses its ability to sustain itself in the face of high levels of activity. Endurance starts to decrease significantly, and during this period, the body becomes less prepared for high levels of physical exertion and gains from exercise start to decline.
Also, the body’s capacity for restorative sleep starts to drop, exacerbating further decline. During the third phase of HGH Deficiency, overall health starts to deteriorate as well. Early in this phase, aesthetic skin health starts to decline rapidly as wrinkles and deep creases start to develop. Cholesterol and Triglyceride levels increase, hypertension often develops as a result of cardiovascular strain and arterial plaques. The body begins to seep calcium from deep within the bones, which inevitably leads to symptoms of osteoporosis over time. During this phase, the body not only responds less readily to exercise, but it will be difficult to make significant gains at all, and in the worst cases, exercise will only serve to prevent muscle atrophy from occurring.
Meet the New You with Sermorelin
Sermorelin Acetate Therapy is a verified safe, effective, and biologically self-containing means to stimulate the pituitary to produce healthy and normal levels of Human Growth Hormone by emulating the effects of GH-RH and Ghrelin on Somatotroph activity. Sermorelin is available at numerous pharmacies across the United States and is generally compounded on-site by a licensed pharmacist. Sermorelin Therapy is not subject to the same restrictions as Bio-Identical Human Growth Hormone, and is available with a physician’s prescription.
Unlike HGH Hormone Replacement Therapy, there are no legal restrictions placed on the prescribing physician in regard to his or her medical expertise and opinion, and as a result, Sermorelin Injections can be prescribed off-label in order to treat many symptoms of HGH Deficiency that have been clinically shown to be beneficial, yet have not yet been approved by the FDA.
After Human Growth Hormone is released into the human body, HGH circulates through the body for a brief period before being mostly converted into a hormone known as IGF-1 in the liver. IGF-1 is the primary vehicle by which Human Growth Hormone affects age-defying characteristics. Increased levels of IGF-1 circulate through the blood and boost the rate by which metabolism occurs, providing increased energy levels to all aspects of physiological function. In addition to this, IGF-1 stimulates the healthy development of new cells within the bones and the various organs throughout the body. This pattern of cellular replacement is normal but slows down significantly as endogenous levels of HGH decline.
Increased levels of Growth Hormone and IGF-1 revamp these muted processes, allowing the body to rebuild itself at a pace that protects human youth and vitality more effectively.
Usual Dosage
Sermorelin Acetate Injection comes in 9 ml vial that we reconstitute with 5 mL of bacteriostatic water. You will use 15 units, or 0.15 mL injection every night before bed.
How do I use Sermorelin?
Sermorelin Acetate is only available via injection. These injections are generally provided once daily before bed, but dependent upon your particular health goals and the advice of your doctor, you may decide to administer your injection either in the morning or before you engage in exercise. Nighttime injections are generally recommended because HGH production primarily occurs during sleep. Dosage will depend upon your individual hormone profile, along with your age and gender.
Should I use Sermorelin or HGH?
Both of these are viable treatment options for patients over the age of thirty. There are fewer restrictions on the usage of Sermorelin Acetate therapy, though both treatment options provide similar potential gains. Some patients claim that HGH produces results at a slightly faster rate than Sermorelin alone.
Sermorelin Acetate Therapy is much more cost-effective than Human Growth Hormone, and negative feedback mechanisms prevent HGH overdose and associated effects.
What are the side effects of Sermorelin?
Sermorelin Acetate has a small risk of side effects. The most common of these are swelling and pain around the injection site. Some other patients experience itching because of injection, or difficulty swallowing. Although these two side-effects are not dangerous, it is important to let your doctor know so that corrective measures can be taken. In very rare cases, other side effects occur, such as vomiting, hyperactivity, headache, and dizziness. These symptoms should be reported to a physician immediately if they occur.
